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  3 Mount Elizabeth
Mt Elizabeth Medical Centre #07-08, Singapore 228510

Tel: +65 6836 5480
Fax: +65 6836 9523

24 hrs Emergency line:
+65 6535 8833

Clinic opening hours:

Monday - Friday:
9am-1pm, 2pm-5pm

Saturday:
9am-1pm

Sunday and Public Holidays:
Closed

 
 
 
PUBLICATIONS IN ENGLISH
  1. Gluteus Maximus Muscle Flaps for Reconstruction of Sacral Chordoma Defects. PK Koh, BK Tan, AG Tay, C Song, KC Tan.Annals of Plastic Surgery, 2004 July, 53(1): 44-59. 
    [http://www.ncbi.nlm.nih.gov/pubmed/15211198

  2. Management of Anal Canal Cancer: A review. H. Sato, P.K. Koh, D.C.C. Bartolo. Diseases of the Colon & Rectum, 2005; 48: 1301-1315.
    [http://www.ncbi.nlm.nih.gov/pubmed/15793642

  3. Total Mesorectal Excision: The Unrecognized Pelvic Plane. Koh PK, Seow-Choen Francis, Kwek BH. Diseases of the Colon & Rectum, 2005; 49: 1-5.
    [http://www.ncbi.nlm.nih.gov/pubmed/16322966

  4. Mucosal Flap Excision for Residual Hemorrhoids or Skin Tags after Stapled Hemorrhoidopexy. P.K Koh, Seow-Choen F.Diseases of the Colon & Rectum 2005; 48: 1660-1662. 
    [http://www.ncbi.nlm.nih.gov/pubmed/15981055

  5. A Systematic Review of the Function and Complications of Colonic Pouches. PK Koh, CL Tang, KW Eu, M Samuel, E Chan.International Journal of Colorectal Diseases 2007; 22(5): 543-548. 
    [http://www.ncbi.nlm.nih.gov/pubmed/16969678

  6. Multicentre Prospective Randomized Trials Are Not Always Relevant To Surgeons. PK Koh, Francis Seow-Choen. ANZ J. Surg. 2006; 76: 286-287.
    [http://www.ncbi.nlm.nih.gov/pubmed/16768681

  7. Mesenteric Desmoid Tumors in Singapore Familial Adenomatous Polyposis Patients: Clinical Course and Genetic Profile in a Predominantly 中文 Population. P.K. Koh, K.W. Eu, C. Loi, X. Cao, P.Y. Cheah, C.L. Tang, B.S. Ooi, K.S. Ho. Diseases of the Colon & Rectum 2007 Jan; 50(1): 75-82.
    [http://www.ncbi.nlm.nih.gov/pubmed/17082890

  8. Laparoscopic Total Proctocolectomy. Video Presentation at SAGES 2007. PK Koh, B Ritson, FH Remzi. Surgical EndoscopyApril 2007, vol 21 (Supp 13).

  9. A novel method of dealing with a large rectal enterotomy in an irradiated pelvis. NY Wong, PK Koh, KW Eu. Techniques in Coloproctology  2007 Dec; Vol 11(4): 350-352.
    [http://www.ncbi.nlm.nih.gov/pubmed/18209949

  10. Phenotypic characteristics of HNPCC by the Amsterdam Criteria: An Asian Perspective. MH Chew, PK Koh, KH Ng, CL Tang, KW Eu. ANZ Journal of Surgery 2008; Vol 78 (7): 556 - 560. 
    [http://www.ncbi.nlm.nih.gov/pubmed/18593409

  11. Modest promoter methylation of E-cadherin gene cannot explain the downregulation of E-cadhedrin protein in sporadic colorectal cancers: A quantitative analysis. Yanqun Liu, Yi Zhao, ChiYu Wu, Kok Sun Ho, Stephanie Fook Chong, Poh Koon Koh, Kong Weng Eu. Cancer Biomarkers 2008; 4(2): 111-112.
    [http://www.ncbi.nlm.nih.gov/pubmed/18503162]

  12. Ileo-Anal J-Pouch Cancer: An Unusual Case in an Unusual Location. PK Koh, J Doumit, E DownsKelly, MP Bronner, R Salimi, JD Vogel. Techniques in Coloproctology 2008 Dec; Vol 12 (4): 341-345. 
    [http://www.ncbi.nlm.nih.gov/pubmed/18545871

  13. Metabolic Profiling of Human Colorectal Cancer using High-Resolution Magic Angle Spinning Nuclear Magnetic Resonance (HR-MAS NMR) Spectroscopy and Gas Chromatography Mass Spectrometry (GC/MS). Eric Chun Yong Chan, Poh Koon Koh, Mainak Mal, Peh Yean Cheah, Kong Weng Eu, Alexandra Backshall, Rachel Cavill, Jeremy K Nicholson, and Hector C Keun.Journal of Proteome Research 2009; 8: 352-361. 
    [http://www.ncbi.nlm.nih.gov/pubmed/19063642]

  14. Development and validation of a gas chromatography/mass spectrometry method for the metabolic profiling of human colon tissue. Mainak Mal, Poh Koon Koh, Peh Yean Cheah and Eric Chun Yong Chan. Rapid Communications in Mass Spectrometry 2009; 23: 487 - 494. 
    [http://www.ncbi.nlm.nih.gov/pubmed/19140133

  15. Improved survival in an Asian cohort of young colorectal cancer patients: an analysis of 523 patients from a single institution. Chew MH, Koh PK, Ng KH, Eu KW. Int J Colorectal Dis 2009; 24(9): 1075-83.
    [http://www.ncbi.nlm.nih.gov/pubmed/19387661

  16. Novel human pathological mutations. Gene symbol: APC. Disease: Adenomatous polyposis coli. Cheah PY, Wong HY, Loi C,Koh PK, Eu KW. Hum Genet 2009 Apr; 125(3): 352. 
    [http://www.ncbi.nlm.nih.gov/pubmed/19320041]

  17. Germline Bone Morphogenesis Protein Receptor 1A Mutation Causes Colorectal Tumorigenesis in Hereditary Mixed Polyposis Syndrome. Peh Yean Cheah, Yu Hui Wong, Yuk Ping Chau, Carol Loi, Kiat Hon Lim, Jit Fong Lim, Poh Koon Koh, Kong Weng Eu. Am J Gastroenterol 2009 Dec; 104(12): 3027-33.
    [http://www.ncbi.nlm.nih.gov/pubmed/19773747

  18. Puertz-Jeghers Syndrome: Data from the Singapore Polyposis Registry and a Shifting Paradigm in Management. Tan KM V,Koh PK, Loi TT, Eu KW, Tang CL. Annals Acad Med Singapore2010; 39: 17-21. 
    [http://www.ncbi.nlm.nih.gov/pubmed/20126809]

  19. Genome-wide scan identifies a copy number variable region at 3q26 that regulates PPM1L in APC mutation-negative familial colorectal cancer patients. Thean LF, Loi C, Ho KS, Koh PK, Eu KW, Cheah PY. Genes Chromosomes Cancer. 2010 Feb; 49(2): 99 – 106. 
    [http://www.ncbi.nlm.nih.gov/pubmed/19847890

  20. Preliminary Results of Mismatch Repair Deficiency Screening via Immunohistochemical Staining in Young Asian Colorectal Cancers. Poh-Koon Koh, Min-Hoe Chew, Yan-Sheng Tan, Kiat-Hon Lim, Carol Loi, Choong-Leong Tang, Kong-Weng Eu.Proceedings of Singapore Healthcare, Volume 19, Number 1, 2010.
    [http://www.singhealthacademy.com.sg/ResourcesAndServices
    /Publications/ProceedingsofSingaporeHealthcare/Pages/
    ProceedingsVolume19Number12010.aspx
    ]

  21. A 'metastasis-prone' signature for early-stage mismatch-repair proficient sporadic colorectal cancer patients and its implications for possible therapeutics. Yi Hong, Thomas Downey, Kong Weng Eu, Poh Koon Koh, Peh Yean Cheah. Clin Exp Metastasis 2010 Feb; 27 (2): 83 – 90.
    [http://www.ncbi.nlm.nih.gov/pubmed/20143136

  22. Critical analysis of mucin and signet ring cell as prognostic factors in an Asian population of 2,764 sporadic colorectal cancers. Chew MH, Yeo SA, Ng ZP, Lim KH, Koh PK, Ng KH, Eu KW. Int J Colorectal Dis. 2010 Oct; 25(10): 1221-9. 
    [http://www.ncbi.nlm.nih.gov/pubmed/20686777]

  23. Ultra-pressure liquid chromatography/tandem mass spectrometry targeted profiling of arachidonic acid and eicosanoids in human colorectal cancer. Mainak Mal, Poh-Koon Koh, Peh Yean Cheah and Eric Chun Yong Chan. Rapid Communications in Mass Spectrometry 2011, 25, 755–764.
    [http://www.ncbi.nlm.nih.gov/pubmed/21337637

  24. Familial colorectal cancer type-X: polyp burden and cancer risk stratification via a family history score. Poh-Koon Koh, Matthew Kalady, Marek Skacel, Susan Fay, Ellen McGannon, Janet Shenal, Loretta Arroyo, Kathy Toderick, James Church. ANZ J Surg2011 Volume 81, Issue 7-8, pages 537–542.
    [http://onlinelibrary.wiley.com/doi/10.1111/
    j.1445-2197.2010.05606.x/abstract
    ]

  25. Stage IV colorectal cancers: an analysis of factors predicting outcome and survival in 728 cases. Chew MH, Koh PK. J Gastrointestinal Surgery 2011.
    [http://www.ncbi.nlm.nih.gov/pubmed/22009464

  26. Macrophages in Human Colorectal Cancer are Pro-inflammatory and Prime T cells towards an Anti-Tumour Type-1 Inflammatory Response. Ong SM, Tan YC, Beretta O, Jiang D, Yeap WH, Tai JJ, Wong WC, Yang H, Schwarz H, Lim KH, Koh PK, Ling KL, Wong SC. Eur J Immunol. 2011 Oct 18. doi: 10.1002/eji.201141825. 
    [http://www.ncbi.nlm.nih.gov/pubmed/22009685]
 
PUBLICATIONS IN CHINESE
  1. “直肠癌复发再手术与单纯辅助治疗的对照研究”。许宝琨、萧俊、彭晓辉。《中国实用外科杂志》2004 年 7 月 第 24 卷 第 7 期,412 - 414页。

  2. “应用齿状线上直肠黏膜瓣切除法处理吻合器痔切除术后残余外痔或皮赘”。许宝琨、彭慧、萧俊。《中华胃肠外科杂志》2006 年 1 月第 9卷 第 1 期,79-80页。

  3. “全直肠系膜切除:未被认识的盆腔平面”。许宝琨、彭慧、萧俊。《中华胃肠外科杂志》2006 年 3 月第 9 卷第 2期, 178 - 179 页。

  4. “纤维与肠道健康:西方医学证据的评价”。许宝琨、蔡慧丽、萧俊。《中华胃肠外科杂志》。

  5. “处理廻肠J囊癌的手术策略与西方文献的综述“。许宝琨、张卫、余光荣。《 中国实用外科杂志》。
 
BOOK CHAPTER
  1. “Management of Anal Canal Cancer” H Sato, PK Koh, DCC Bartolo. Selected Readings in General Surgery 2007, Volume 34 (7).


 
 
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